Safe-T-Vue

Instructions

Triple-Dye

  1. Slide the ampule out of the sleeve.
  2. Rotate the ampule and slide it fully back into the sleeve so the Bio-Filter Tip™ is exposed.
  3. Simply squeeze the sleeve at the dot printed on it to break the ampule.
  4. With the tip pointed downward, squeeze ampule gently to saturate the tip. You are now ready to apply Triple-Dye.

Note: For drop application, follow step 3 by squeezing ampule again to allow drops to fall directly on area.

Triple-dye is non-sensitizing: visibly indicates where the medication was applied. No contra-indications.

Each ML contains:
Brilliant green 2.29 mg., proflavine hemisulfate, 1.14 mg., gentian violet 2.29 mg., in distilled water.

Care of the Umbilical Cord

A brief review of the literature*

World Health Organization (WHO)

Triple dye is a combination of brilliant green (2.29 mg/ml), proflavine hemisulfate (1.14 mg/ml) and gentian violet (2.29 mg/ml). It is bacteriostatic against gram-positive bacteria but less effective against gram-negative bacteria. It is fungicidal but has weak virucidal activity and is not sporicidal. It colours the skin bright purple. Triple dye has the advantage of a prolonged antibacterial effect after a single application.

In several studies, triple dye was found to be more effective in reducing umbilical colonization by staphylococcal and streptococcal organisms in hospital nurseries than :

Alcohol, Pages B. Jones C C: An audit of the effective two cord care regimens on bacteria colonization in new born infants. Quality Review Bulletin 1987 13(3): 109-113

Hexachlorophene, Pildes R S et al: Effect of Triple Dye on staphylococcal colonization in the newborn infant. Journal of Pediatrics 1973 82: 987-990

Bacitracin ointment, Andrich M P, Golden S M: A study of bacitrin ointment vs. Triple Dye. Clinical Pediatrics 1984 23:342-344

Povidone-iodine, Deloache W et al: Prophylactic treatment of umbilical stump: comparison of techniques. Southern Medical Journal 1976, 619-627

Triple Dye is effective even if applied only once. Triple dye has also been shown to reduce colonization by Methicillin-Resistant Staphylococcus Aureus (MRSA) although it could not totally eradicate the organism.

* This is a reproduction of an article published by the World Health Organization, Geneva, Switzerland 1999